منابع مشابه
Symmetry-breaking motility.
Locomotion of bacteria by actin polymerization and in vitro motion of spherical beads coated with a protein catalyzing polymerization are examples of active motility. Starting from a simple model of forces locally normal to the surface of a bead, we construct a phenomenological equation for its motion. The singularities at a continuous transition between moving and stationary beads are shown to...
متن کاملWhere to Go: Breaking the Symmetry in Cell Motility
Cell migration in the "correct" direction is pivotal for many biological processes. Although most work is devoted to its molecular mechanisms, the cell's preference for one direction over others, thus overcoming intrinsic random motility, epitomizes a profound principle that underlies all complex systems: the choice of one axis, in structure or motion, from a uniform or symmetric set of options...
متن کاملIn Silico Reconstitution of Actin-Based Symmetry Breaking and Motility
Eukaryotic cells assemble viscoelastic networks of crosslinked actin filaments to control their shape, mechanical properties, and motility. One important class of actin network is nucleated by the Arp2/3 complex and drives both membrane protrusion at the leading edge of motile cells and intracellular motility of pathogens such as Listeria monocytogenes. These networks can be reconstituted in vi...
متن کاملCorrection: Where to Go: Breaking the Symmetry in Cell Motility
[This corrects the article DOI: 10.1371/journal.pbio.1002463.].
متن کاملActin-based motility: cooperative symmetry-breaking and phases of motion.
A microscopic model is proposed for the motility of a bead driven by the polymerization of actin filaments. The model exhibits a rich spectrum of behaviours similar to those observed in biomimetic experiments, which include spontaneous symmetry-breaking, various regimes of the bead's motion and correlations between the structure of the actin tail which propels the bead and the bead dynamics. Th...
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ژورنال
عنوان ژورنال: Physical Review Letters
سال: 2005
ISSN: 0031-9007,1079-7114
DOI: 10.1103/physrevlett.95.138101